Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723108 | 1.00 | HDAC6 (0.41) | HDAC6PTGER4RXFP1BCAT1ALDH1A1 | |
| SCHEMBL24313562 | 0.89 | NPC1 (0.46) | HDAC6PTGER4BCAT1ALDH1A1KDM4E | |
| SCHEMBL31723075 | 0.88 | HDAC6 (0.41) | HDAC6PTGER4BCAT1ALDH1A1KDM4E | |
| SCHEMBL24313739 | 0.88 | HDAC6 (0.41) | HDAC6PTGER4BCAT1ALDH1A1KDM4E | |
| SCHEMBL22601140 | 0.87 | SLC16A3 (0.42) | PTGER4BCAT1ALDH1A1KDM4EMEN1 | |
| SCHEMBL24313791 | 0.85 | KDM4E (0.51) | PTGER4BCAT1ALDH1A1KDM4EMEN1 | |
| SCHEMBL31723074 | 0.85 | KDM4E (0.51) | PTGER4BCAT1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22588194 | 0.85 | PTGER4 (0.39) | PTGER4BCAT1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22588427 | 0.84 | BCAT1 (0.43) | PTGER4BCAT1ALDH1A1KDM4EMEN1 | |
| SCHEMBL30538408 | 0.84 | BCAT1 (0.55) | BCAT1ALDH1A1KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |