Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273994 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL29772252 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30057569 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23313056 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23273738 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23273855 | 0.79 | HTR3A (0.47) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL24313570 | 0.79 | HRH3 (0.48) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23273985 | 0.77 | HTR3A (0.46) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30824499 | 0.76 | HRH3 (0.71) | CYP1A2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23273977 | 0.75 | PIM1 (0.48) | CYP1A2HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |