Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.55 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.52 |
| ▸ | FXR2 | P51116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313890 | 0.97 | NR1H4 (0.55) | NR1H4HSD17B13FXR2 | |
| SCHEMBL23474085 | 0.94 | NR1H4 (0.59) | NR1H4HSD17B13FXR2 | |
| SCHEMBL32675666 | 0.94 | NR1H4 (0.59) | NR1H4HSD17B13FXR2 | |
| SCHEMBL24313807 | 0.93 | NR1H4 (0.54) | NR1H4HSD17B13FXR2 | |
| SCHEMBL24313806 | 0.92 | NR1H4 (0.63) | NR1H4HSD17B13FXR2 | |
| SCHEMBL24313821 | 0.89 | NR1H4 (0.63) | NR1H4HSD17B13FXR2 | |
| SCHEMBL23474094 | 0.87 | NR1H4 (0.54) | NR1H4HSD17B13FXR2 | |
| SCHEMBL23474090 | 0.86 | NR1H4 (0.53) | NR1H4HSD17B13FXR2 | |
| SCHEMBL23474096 | 0.86 | NR1H4 (0.69) | NR1H4HSD17B13FXR2 | |
| SCHEMBL25209031 | 0.85 | NR1H4 (0.68) | NR1H4HSD17B13FXR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022077161-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |