Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 16/20 | 0.78 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.70 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.70 |
| ▸ | FLT3 | P36888 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313609 | 0.88 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL24313514 | 0.87 | PRMT5 (0.91) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL29611145 | 0.87 | PRMT5 (0.91) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL24314160 | 0.85 | METTL3 (0.75) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL24314281 | 0.85 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL24313867 | 0.83 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL24313546 | 0.83 | METTL3 (1.00) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL24313569 | 0.82 | METTL3 (1.00) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL24313694 | 0.82 | METTL3 (0.74) | METTL3PRMT5WDR77FLT3 | |
| SCHEMBL24313884 | 0.82 | PRMT5 (0.83) | METTL3PRMT5WDR77FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |