SCHEMBL24314490

SCHEMBL24314490

C1=Cc2c(oc3cc(-c4ccc5oc6cccc(-c7nc(-c8ccccc8)nc(-c8ccc(-c9ccccc9)cc8)n7)c6c5c4)ccc23)CC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.32
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24314457 0.91 KDM4E (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL24971407 0.91 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL24033375 0.90
SCHEMBL22924336 0.90 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL25652589 0.89 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL24972790 0.89 PRKDC (0.36) PRKDC
SCHEMBL26333215 0.89 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL21755976 0.89 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10
SCHEMBL29307020 0.88
SCHEMBL26420695 0.88 BACE1 (0.32) PLA2G2APLA2G4APLA2G10PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed