SCHEMBL24314827

SCHEMBL24314827

C1=Cc2cccc(-c3nc(-c4ccccc4)nc(-c4cccc5oc6ccc(-c7ccccc7)cc6c45)n3)c2CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PRKDC P78527 2/20 0.33
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
PLA2G10 O15496 1/20 0.32
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TSHR P16473 1/20 0.30
TBK1 Q9UHD2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24971096 0.88 TSHR (0.31) TSHR
SCHEMBL24973226 0.87 PRKDC (0.30) PRKDC
SCHEMBL24971102 0.86 BACE1 (0.31) L3MBTL1TSHR
SCHEMBL26401188 0.85
SCHEMBL25837617 0.85 PRKDC (0.33) PRKDC
SCHEMBL25831164 0.85 BACE1 (0.31) TSHR
SCHEMBL23821094 0.84 PLA2G2A (0.43) PLA2G2APLA2G4APRKDCPIM1CSNK2A2
SCHEMBL24840982 0.84 PLA2G2A (0.43) PLA2G2APLA2G4APRKDCPIM1CSNK2A2
SCHEMBL23820239 0.84 PLA2G2A (0.43) PLA2G2APLA2G4APRKDCPIM1CSNK2A2
SCHEMBL23822619 0.84 PLA2G2A (0.43) PLA2G2APLA2G4APRKDCPIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed