SCHEMBL24315009

SCHEMBL24315009

C1=CC(c2nc(-c3ccc4ccccc4c3)nc(-c3cccc4oc5c(-c6cc7c8ccccc8oc7c7ccccc67)cccc5c34)n2)=CCC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 5/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26067832 0.91 PRKDC (0.35) ALOX5PRKDC
SCHEMBL26288559 0.91 PRKDC (0.32) ALOX5PRKDC
SCHEMBL25834591 0.90 ALOX5 (0.38) ALOX5PRKDC
SCHEMBL24971657 0.90 ALOX5 (0.38) ALOX5PRKDC
SCHEMBL24655067 0.89 PRKDC (0.32) ALOX5PRKDC
SCHEMBL26067040 0.88 PRKDC (0.35) ALOX5PRKDC
SCHEMBL24658277 0.88 PRKDC (0.32) PRKDC
SCHEMBL23820527 0.87 PRKDC (0.36) ALOX5PRKDC
SCHEMBL26068070 0.86 PRKDC (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL26041667 0.86 ALOX5 (0.34) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed