Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210072 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL17410370 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL2017698 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL17826767 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL22402324 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL10831915 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL23696190 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL14601752 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL939536 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 | |
| SCHEMBL12640200 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |