SCHEMBL24315602

SCHEMBL24315602

N/C(=N\C(=N/Cc1cccc2oc3cc(-c4ccccc4)ccc3c12)c1ccc2ccc(-c3ccccc3)cc2c1)c1ccc2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 5/20 0.41
GRIN1 Q05586 4/20 0.41
HTR2B P41595 1/20 0.33
ANO1 Q5XXA6 1/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25653733 0.95 GRIN2B (0.35) GRIN2BGRIN1HTR2BMMP12MMP13
SCHEMBL24314853 0.94 GRIN1 (0.43) GRIN2BGRIN1HTR2BMMP12MMP13
SCHEMBL26283753 0.91 GRIN2B (0.45) GRIN2BGRIN1HTR2BANO1
SCHEMBL24315350 0.91 GRIN2B (0.44) GRIN2BGRIN1HTR2BANO1ESR1
SCHEMBL26068651 0.90 GRIN2B (0.37) GRIN2BGRIN1HTR2B
SCHEMBL26382253 0.90 GRIN2B (0.41) GRIN2BGRIN1HTR2BANO1MMP12
SCHEMBL26042407 0.89 GRIN2B (0.38) GRIN2BGRIN1HTR2BANO1MMP12
SCHEMBL24971099 0.87 GRIN2B (0.41) GRIN2BGRIN1HTR2BANO1
SCHEMBL26068028 0.86 GRIN1 (0.40) GRIN2BGRIN1HTR2BANO1MMP12
SCHEMBL24314844 0.85 HTR2B (0.34) GRIN2BGRIN1HTR2BMMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2023-06-21 EP disclosed
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed