SCHEMBL24314844

SCHEMBL24314844

N/C(=N\C(=N/Cc1cccc2oc3cc(-c4ccc5c(ccc6ccccc65)c4)ccc3c12)c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.34
PDPK1 O15530 1/20 0.32
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2B Q13224 2/20 0.32
SCN5A Q14524 1/20 0.31
SCN2A Q99250 1/20 0.31
HCRTR1 O43613 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24314853 0.91 GRIN1 (0.43) HTR2BMMP12MMP13GRIN1GRIN2B
SCHEMBL23822478 0.90 HTR2B (0.36) HTR2BMMP12MMP13GRIN1GRIN2B
SCHEMBL25651588 0.88 ALOX5 (0.35) PDPK1GRIN1GRIN2B
SCHEMBL25653733 0.88 GRIN2B (0.35) HTR2BMMP12MMP13GRIN1GRIN2B
SCHEMBL24315035 0.87 GRIN2B (0.39) HTR2BGRIN1GRIN2B
SCHEMBL20391959 0.86 GRIN2B (0.34) HTR2BGRIN1GRIN2B
SCHEMBL26068028 0.85 GRIN1 (0.40) HTR2BMMP12MMP13GRIN1GRIN2B
SCHEMBL24315602 0.85 GRIN2B (0.41) HTR2BMMP12MMP13GRIN1GRIN2B
SCHEMBL26041058 0.85 HTR2B (0.35) HTR2BMMP12MMP13KDM4EMAPT
SCHEMBL24315350 0.85 GRIN2B (0.44) HTR2BGRIN1GRIN2BSCN5ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2023-06-21 EP disclosed
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed