SCHEMBL24316732

SCHEMBL24316732

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nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14895464 0.83 TDP1 (0.40) TDP1TSHR
SCHEMBL18653753 0.83 TDP1 (0.40) TDP1TSHR
SCHEMBL14469398 0.83 TDP1 (0.40) TDP1TSHR
SCHEMBL13770693 0.83 TDP1 (0.40) TDP1TSHR
SCHEMBL13070334 0.82 TDP1 (0.35) TDP1TSHR
SCHEMBL18934170 0.82 TDP1 (0.35) TDP1TSHR
SCHEMBL19277005 0.82 TDP1 (0.35) TDP1TSHR
SCHEMBL20143360 0.82 TDP1 (0.35) TDP1TSHR
SCHEMBL14845686 0.81 TDP1 (0.38) TDP1TSHR
SCHEMBL15357334 0.81 TDP1 (0.38) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220081482-A1 ANTICANCER COMPOSITIONS COMPRISING IMMUNE CHECKPOINT INHIBITORS NOAHM INC. (KR) 2022-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081482-A1 ANTICANCER COMPOSITIONS COMPRISING IMMUNE CHECKPOINT INHIBITORS ITPA, IP6K1, IP6K3 TDP1 881/4885TSHR 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.