IP6K3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2492556	0.57	9/20
SCHEMBL2505118	0.49	6/20
SCHEMBL2505119	0.49	6/20
SCHEMBL3348016	0.41	6/20
SCHEMBL2191067	0.69	5/20
SCHEMBL182871	0.54	5/20
SCHEMBL216176	0.54	5/20
SCHEMBL642178	0.54	5/20
SCHEMBL1507614	0.54	5/20
SCHEMBL2081677	0.54	5/20
SCHEMBL2191006	0.54	5/20
SCHEMBL263154	0.54	5/20
SCHEMBL1360723	0.52	5/20
SCHEMBL858674	0.50	5/20
SCHEMBL2118498	0.50	5/20
SCHEMBL158065	0.49	5/20
SCHEMBL858781	0.49	5/20
SCHEMBL496981	0.44	5/20
SCHEMBL157952	0.43	5/20
SCHEMBL2426171	0.60	4/20

Clinical trials — most relevant to IP6K3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway	PHASE4	COMPLETED
Effect of a Basal/Pre-Meal Insulin Strategy (Detemir/Aspart) on Insulin Secretion and Action in Type 2 Diabetes	PHASE4	COMPLETED
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity	PHASE4	COMPLETED
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus	PHASE3	UNKNOWN
Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate	PHASE2/PHASE3	WITHDRAWN
Efficacy of Lithium Against Chemotherapy Induced Neutropenia in Breast Cancer Patients	PHASE3	COMPLETED
Inositol in Letrozol Resistant PCOS Women	PHASE2/PHASE3	COMPLETED
A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects	PHASE2	COMPLETED
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes	PHASE2	RECRUITING
Analysis of Tissues From Patients in Trial of Myo-Inositol to Prevent Lung Cancer	PHASE1	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans	PHASE1	COMPLETED
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer	EARLY_PHASE1	COMPLETED
The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity.	nan	UNKNOWN
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome	nan	COMPLETED
Duality of Lipids: the Athlete's Paradox	nan	COMPLETED
The Effect of Blueberries on Enhancing Insulin Sensitivity in Humans: A Pilot Study	nan	WITHDRAWN
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia	nan	UNKNOWN
p-AKT Expression on Clinical Outcomes in Malignant Lymphoma	nan	COMPLETED
Myoinositol Treatment and Asprosin Levels in PCOS	nan	COMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia	nan	RECRUITING
Metabolic Signalling in Muscle- and Adipose-tissue Following Insulin Withdrawal and Growth Hormone Injection.	nan	COMPLETED
Free Fatty Acid Induced Insulin Resistance	nan	COMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation	nan	COMPLETED
Dried Fruit and Postprandial Glycemia Trial	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Vulvodynia: Identification of Potential Relevant Biomarkers	nan	COMPLETED
Partial PTEN Deletion in Breast Cancer	nan	UNKNOWN
The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients	nan	UNKNOWN
Protein Intake and Step Reduction in Older Adults	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a IP6K3 binder may also engage these)

Protein	Name	Similarity
Q8BWD2	—	1.000	Q8BWD2 →
Q80V72	—	0.983	Q80V72 →
Q9R0U1	—	0.982	Q9R0U1 →
Q95221	—	0.975	Q95221 →
IP6K2	Inositol hexakisphosphate kinase 2	0.973	landscape →
Q99NI4	—	0.971	Q99NI4 →
Q14CH1	—	0.965	Q14CH1 →
Q7TT16	—	0.964	Q7TT16 →
P97616	—	0.959	P97616 →
Q92502	—	0.959	Q92502 →
P17105	—	0.959	P17105 →
Q9D2Q2	—	0.958	Q9D2Q2 →
Q61161	—	0.958	Q61161 →
MAP4K2	Mitogen-activated protein kinase kinase kinase kinase 2	0.957	landscape →
F1QWK4	—	0.957	F1QWK4 →
Q96MI9	—	0.956	Q96MI9 →
Q8BML1	—	0.955	Q8BML1 →
Q9JI20	—	0.955	Q9JI20 →
Q3U269	—	0.955	Q3U269 →
Q7ZU92	—	0.954	Q7ZU92 →
Q3UKU4	—	0.953	Q3UKU4 →
O43379	—	0.953	O43379 →
P59679	—	0.953	P59679 →
Q9NS39	—	0.953	Q9NS39 →
Q4R6L3	—	0.953	Q4R6L3 →
Q148G5	—	0.953	Q148G5 →
Q96EN8	—	0.953	Q96EN8 →
P70218	—	0.953	P70218 →
IPMK	Inositol polyphosphate multikinase	0.952	landscape →
Q8CHT6	—	0.952	Q8CHT6 →