Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 9/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538950 | 1.00 | S1PR4 (0.39) | S1PR4HSPB1NPC1RAB9AALDH1A1 | |
| SCHEMBL5582989 | 0.85 | S1PR4 (0.41) | S1PR4HSPB1NPC1RAB9AALDH1A1 | |
| SCHEMBL30271367 | 0.79 | S1PR4 (0.36) | S1PR4HSPB1NPC1RAB9AALDH1A1 | |
| SCHEMBL3024826 | 0.74 | ATM (0.44) | S1PR4HSPB1ALDH1A1KDM4EMAPT | |
| SCHEMBL3770753 | 0.72 | MAPT (0.45) | S1PR4HSPB1ALDH1A1MAPTLMNA | |
| SCHEMBL5582938 | 0.72 | MAPK1 (0.36) | HSPB1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL28874590 | 0.72 | PDE7A (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2383985 | 0.72 | MAPT (0.34) | S1PR4HSPB1ALDH1A1KDM4EMAPT | |
| SCHEMBL823564 | 0.72 | MEN1 (0.34) | S1PR4HSPB1KDM4EMAPTLMNA | |
| SCHEMBL27848440 | 0.72 | MAPT (0.34) | S1PR4HSPB1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092774-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2024-03-21 | — | — | US | disclosed |
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092774-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | CYP2D6, CYP3A7, CYP2F1 | S1PR4 4372/4885HSPB1 3298/4885NPC1 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.