Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006794 | 0.86 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2SLC5A2ABCB11 | |
| SCHEMBL20006831 | 0.83 | SLC6A2 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL24317252 | 0.83 | SLC6A2 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL24317060 | 0.75 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL15325843 | 0.74 | F2RL1 (0.41) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL20175293 | 0.74 | ABCB1 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL14719246 | 0.72 | F2RL1 (0.40) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL19658854 | 0.71 | TYR (0.44) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL27454261 | 0.70 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL18255051 | 0.70 | SLC6A2 (0.51) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |