Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317253 | 0.75 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3TAAR1 | |
| SCHEMBL15325843 | 0.74 | F2RL1 (0.41) | SLC6A4SLC6A2SLC6A3TAAR1HTR2A | |
| SCHEMBL23940698 | 0.73 | TAAR1 (0.47) | SLC6A4SLC6A2SLC6A3TAAR1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL14719246 | 0.72 | F2RL1 (0.40) | SLC6A4SLC6A2SLC6A3TAAR1HTR2A | |
| SCHEMBL20204829 | 0.71 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3CHRM3 | |
| SCHEMBL19658854 | 0.71 | TYR (0.44) | SLC6A4SLC6A2SLC6A3TAAR1HTR2A | |
| SCHEMBL27454261 | 0.70 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3FFAR4TAAR1 | |
| SCHEMBL18255051 | 0.70 | SLC6A2 (0.51) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8240380 | 0.69 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL8508121 | 0.69 | TAAR1 (0.37) | SLC6A4SLC6A2SLC6A3TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |