Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL2431729

O=C1C=C(S)C(=O)N1.O=C1C=C(S)C(=O)N1.S

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.32
GSK3A P49840 1/20 0.32
CCR6 P51684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163390 0.97
Water SCHEMBL6094681 0.94 GSK3B (0.32) GSK3BGSK3ACCR6
SCHEMBL8858121 0.87 GSK3A (0.52) GSK3BGSK3ACCR6
SCHEMBL9587810 0.67 GSK3B (0.37) GSK3BGSK3ACCR6
Benzene SCHEMBL27617257 0.65 GSK3B (0.31) GSK3BGSK3ACCR6
Benzene SCHEMBL28483360 0.65 GSK3B (0.31) GSK3BGSK3ACCR6
SCHEMBL1163904 0.63
SCHEMBL678979 0.63
SCHEMBL36967 0.63
SCHEMBL1029298 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2875357-A1 THERANOSTIC METHOD BASED ON THE DETECTION OF HER2-HER2 DIMERS Cisbio Bioassays (FR) 2015-05-27 EP disclosed
WO-2014013180-A1 THERANOSTIC METHOD BASED ON THE DETECTION OF HER2-HER2 DIMERS CISBIO BIOASSAYS (FR) 2014-01-23 WO disclosed
EP-2364318-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION Bio-Rad Laboratories, Inc. (US) 2011-09-14 EP disclosed
WO-2010065514-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION BIO-RAD LABORATORIES, INC. (US) 2010-06-10 WO disclosed
EP-1874790-A2 NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES RWTH Aachen (DE) 2008-01-09 EP disclosed
WO-2006108678-A2 NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES RWTH AACHEN (DE) 2006-10-19 WO disclosed