Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 4/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011219 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4RECQLCHRNA7DRD2 | |
| SCHEMBL24316297 | 0.75 | PRCP (0.60) | CHRNB2CHRNA4RECQLCHRNA7PRCP | |
| SCHEMBL5820697 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4RECQLCHRNA7PRCP | |
| SCHEMBL27919615 | 0.71 | CHRNB2 (0.43) | CHRNB2CHRNA4RECQLCHRNA7PRCP | |
| SCHEMBL1010980 | 0.68 | CHRNB2 (0.47) | CHRNB2CHRNA4RECQLSIGMAR1DRD2 | |
| SCHEMBL13348988 | 0.68 | CHRNB2 (0.56) | CHRNB2CHRNA4RECQLCHRNA7SIGMAR1 | |
| SCHEMBL1615700 | 0.67 | CHRNB2 (0.50) | CHRNB2CHRNA4RECQLCHRNA7PRCP | |
| SCHEMBL3964346 | 0.66 | KDM1A (0.58) | RECQLPRCPGAA | |
| SCHEMBL27010603 | 0.66 | PRCP (0.60) | CHRNB2CHRNA4RECQLCHRNA7PRCP | |
| SCHEMBL29870802 | 0.65 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7FDPSSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |