Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | FRK | P42685 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067971 | 0.89 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL17541733 | 0.82 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL16014069 | 0.82 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL15330967 | 0.78 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL19428036 | 0.76 | PTGS1 (0.49) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 | |
| SCHEMBL24317555 | 0.74 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL20401786 | 0.72 | MAPK13 (0.46) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL11587705 | 0.72 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17948203 | 0.72 | NPC1 (0.57) | NPC1RAB9AMAPK14MAPK13MAPK12 | |
| SCHEMBL12841350 | 0.72 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2KDM4EMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | Suzhou Fude Zhaofeng Biochemical Technology Co., Ltd (CN) | 2022-08-11 | — | — | US | disclosed |
| WO-2022052391-A1 | METHOD FOR SYNTHESIZING VORTIOXETINE | 苏州富德兆丰生化科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | PIR, CYP2B6, CYP26B1 | NPC1 4365/4885RAB9A 4409/4885SMN1; SMN2 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.