Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316065 | 0.93 | L3MBTL1 (0.52) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620364 | 0.86 | L3MBTL1 (0.51) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL27010441 | 0.84 | L3MBTL1 (0.49) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620046 | 0.83 | TSHR (0.53) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL27010379 | 0.83 | L3MBTL1 (0.48) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620363 | 0.83 | TSHR (0.52) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620204 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620049 | 0.82 | L3MBTL1 (0.49) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620352 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL26620501 | 0.81 | TSHR (0.52) | L3MBTL1MAPTTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |