SCHEMBL24318092

SCHEMBL24318092

CCOC(=O)C1CC1C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.44
CA2 P00918 8/20 0.44
CA12 O43570 6/20 0.44
CA9 Q16790 6/20 0.44
GAA P10253 2/20 0.43
CAPN9 O14815 1/20 0.43
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14671466 1.00 CA1 (0.44) CA1CA2CA12CA9GAA
SCHEMBL16001854 1.00 CA1 (0.44) CA1CA2CA12CA9GAA
SCHEMBL1296897 0.91 ALDH1A1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL8914013 0.91 ALDH1A1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL2705851 0.91 ALDH1A1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL2705849 0.91 ALDH1A1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL12943060 0.91 ALDH1A1 (0.48) CA1CA2CA12CA9GAA
SCHEMBL9656173 0.86 PPM1B (0.49) CA1CA2CA12CA9GAA
SCHEMBL16349313 0.86 PPM1B (0.46) CA1CA2CA12CA9CAPN9
SCHEMBL21950900 0.85 TP53 (0.47) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022041462-A1 SYNTHESIS METHOD FOR CYCLOPROPANE COMPOUND 凯莱英生命科学技术(天津)有限公司 2022-03-03 WO disclosed