Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762835 | 0.81 | HDAC6 (0.32) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL12667928 | 0.81 | CTSS (0.32) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL13534084 | 0.77 | HDAC6 (0.35) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL18419554 | 0.75 | HDAC6 (0.34) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL18658421 | 0.75 | HDAC6 (0.34) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL18400312 | 0.74 | CA14 (0.36) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL25650969 | 0.74 | HDAC6 (0.33) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL27471031 | 0.73 | HDAC6 (0.39) | CTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL15413915 | 0.72 | MEN1 (0.33) | CTSSCTSKHDAC1HDAC2HDAC6 | |
| SCHEMBL18494386 | 0.72 | HDAC6 (0.33) | HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081469-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2022-04-21 | — | — | WO | disclosed |