Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 19/20 | 0.63 |
| ▸ | BMPR1A | P36894 | 19/20 | 0.63 |
| ▸ | TGFBR1 | P36897 | 19/20 | 0.63 |
| ▸ | ACVRL1 | P37023 | 19/20 | 0.63 |
| ▸ | ACVR1 | Q04771 | 19/20 | 0.63 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027200 | 0.93 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL27407318 | 0.93 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21027488 | 0.93 | BMPR1B (0.66) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21026978 | 0.87 | BMPR1B (0.69) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21027936 | 0.85 | BMPR1B (0.69) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23418649 | 0.85 | BMPR1B (0.60) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19806891 | 0.85 | BMPR1B (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23418441 | 0.83 | BMPR1B (0.68) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21027223 | 0.82 | BMPR1B (0.67) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL22456040 | 0.81 | BMPR1B (0.68) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971177-A1 | AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS | Novartis AG (CH) | 2022-03-23 | — | — | EP | disclosed |