Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676953 | 0.81 | EPHX1 (0.45) | ALDH1A1KDM4EEPHX1USP2TSHR | |
| SCHEMBL27590750 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EEPHX1USP2TSHR | |
| SCHEMBL7158082 | 0.78 | EPHX1 (0.42) | ALDH1A1KDM4EEPHX1TSHRADH1B | |
| SCHEMBL28099092 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EEPHX1USP2TSHR | |
| SCHEMBL27951235 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EEPHX1USP2TSHR | |
| SCHEMBL222261 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EEPHX1USP2TSHR | |
| SCHEMBL9335245 | 0.75 | EPHX1 (0.48) | ALDH1A1KDM4EEPHX1TSHRLMNA | |
| SCHEMBL27489037 | 0.75 | EPHX1 (0.48) | ALDH1A1KDM4EEPHX1TSHRLMNA | |
| SCHEMBL28300972 | 0.75 | EPHX1 (0.48) | ALDH1A1KDM4EEPHX1TSHRLMNA | |
| SCHEMBL15279337 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4EEPHX1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050742-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2022067106-A1 | CRYSTALLINE POLYMORPH FORM A OF A JAK INHIBITOR AND METHODS FOR ITS PREPARATION | ACLARIS THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |