Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28125118 | 0.76 | SHBG (0.76) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL8775091 | 0.74 | SHBG (0.46) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL11802672 | 0.72 | SHBG (0.76) | SHBGSMN1; SMN2EPHX1 | |
| SCHEMBL22068456 | 0.72 | SHBG (0.76) | SHBGSMN1; SMN2EPHX1 | |
| SCHEMBL7761672 | 0.70 | SHBG (0.52) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL1094949 | 0.70 | SHBG (0.52) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL29098458 | 0.69 | SHBG (0.56) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL3037218 | 0.69 | EPHX1 (0.50) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL23522672 | 0.69 | SHBG (0.50) | SHBGSMN1; SMN2EPHX1CYP1A2 | |
| SCHEMBL10582810 | 0.69 | EPHX1 (0.50) | SHBGSMN1; SMN2EPHX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051596-A1 | BICYCLIC-HETEROCYCLE DERIVATIVES AND THEIR USES AS OREXIN-2 RECEPTOR AGONISTS | OREXIA THERAPEUTICS LIMITED (GB) | 2022-03-10 | — | — | WO | disclosed |