Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109602 | 0.74 | LMNA (0.41) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL18843589 | 0.72 | KDM4E (0.41) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL840146 | 0.72 | KDM4E (0.41) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL24733235 | 0.72 | KDM4E (0.41) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL12811721 | 0.72 | CHRNA7 (0.42) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL7600492 | 0.69 | KDM4E (0.39) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL14038121 | 0.69 | KDM4E (0.39) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL22920544 | 0.69 | KDM4E (0.39) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL18965040 | 0.68 | KDM4E (0.48) | KDM4ENPC1LMNAALOX15HTT | |
| SCHEMBL21037219 | 0.68 | KDM4E (0.38) | KDM4ENPC1LMNAALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078407-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |