Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24537044 | 0.85 | CHRM1 (0.38) | F2RL1 | |
| SCHEMBL2648922 | 0.76 | F2RL1 (0.41) | F2RL1DGAT1 | |
| SCHEMBL23337421 | 0.75 | F2RL1 (0.40) | F2RL1DGAT1 | |
| SCHEMBL19332396 | 0.75 | F2RL1 (0.42) | F2RL1DGAT1 | |
| SCHEMBL28410869 | 0.75 | ATR (0.35) | F2RL1DGAT1ATRATRIPKLKB1 | |
| SCHEMBL20301731 | 0.72 | DGAT1 (0.34) | DGAT1KLKB1 | |
| SCHEMBL30605723 | 0.72 | F2RL1 (0.38) | F2RL1DGAT1 | |
| SCHEMBL3174588 | 0.72 | F2RL1 (0.40) | F2RL1DGAT1 | |
| SCHEMBL24320457 | 0.71 | DGAT1 (0.34) | DGAT1KLKB1 | |
| SCHEMBL14298916 | 0.71 | F2RL1 (0.42) | F2RL1DGAT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078407-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |