Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870 | 0.79 | UHRF1 (0.50) | UHRF1DYRK1ASMARCA2SMARCA4CCR1 | |
| SCHEMBL29375940 | 0.79 | UHRF1 (0.50) | UHRF1DYRK1ASMARCA2SMARCA4CCR1 | |
| SCHEMBL22954215 | 0.79 | LOX (0.44) | DYRK1ACCR1CCR5CCR8S1PR1 | |
| SCHEMBL18595956 | 0.79 | LOXL2 (0.36) | DYRK1ACCR1CCR5CCR8 | |
| SCHEMBL27812389 | 0.79 | UHRF1 (0.35) | UHRF1DYRK1A | |
| Hydrochloric Acid SCHEMBL4214269 | 0.78 | UHRF1 (0.48) | UHRF1DYRK1ASMARCA2SMARCA4CCR1 | |
| Hydrochloric Acid SCHEMBL29957591 | 0.78 | UHRF1 (0.48) | UHRF1DYRK1ASMARCA2SMARCA4CCR1 | |
| SCHEMBL1118010 | 0.76 | UHRF1 (0.36) | UHRF1DYRK1A | |
| SCHEMBL16825623 | 0.73 | CYP1A2 (0.33) | — | |
| SCHEMBL14703764 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436450-B1 | REACTION MEDIUM CONTAINING WATER-SURFACTANT MIXTURE | NOVARTIS AG (CH) | 2022-03-09 | — | — | EP | disclosed |