Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24323660 | 0.95 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1MAPTGAA | |
| SCHEMBL24323644 | 0.94 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1MAPTGAA | |
| SCHEMBL23201076 | 0.81 | DRD2 (0.39) | SMN1; SMN2MAPTFPR3FPR2IKBKB | |
| SCHEMBL23201079 | 0.81 | DRD2 (0.39) | SMN1; SMN2MAPTFPR3FPR2IKBKB | |
| SCHEMBL24322789 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1MAPTGAA | |
| SCHEMBL2937827 | 0.77 | CYP2D6 (0.42) | SMN1; SMN2MAPTFPR3FPR2IKBKB | |
| SCHEMBL14919306 | 0.77 | CYP2D6 (0.42) | SMN1; SMN2MAPTFPR3FPR2IKBKB | |
| SCHEMBL3335001 | 0.77 | CYP2D6 (0.42) | SMN1; SMN2MAPTFPR3FPR2IKBKB | |
| SCHEMBL28532872 | 0.77 | DRD2 (0.44) | SMN1; SMN2FPR3FPR2IKBKBDRD2 | |
| SCHEMBL28532873 | 0.77 | DRD2 (0.44) | SMN1; SMN2FPR3FPR2IKBKBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | SMN1; SMN2 4226/4885RAB9A 435/4885NPC1 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.