Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.43 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359074 | 1.00 | RECQL (0.48) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL14211272 | 0.98 | RECQL (0.46) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL14120156 | 0.94 | RECQL (0.46) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL30359086 | 0.90 | RECQL (0.50) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL30359137 | 0.88 | RECQL (0.47) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL30359115 | 0.84 | RECQL (0.47) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL14211237 | 0.81 | PIK3CD (0.42) | RECQLTSHRCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL30359032 | 0.80 | RECQL (0.41) | RECQLTSHRALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL19649734 | 0.79 | CHRNB2 (0.50) | RECQLTSHRCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22299286 | 0.79 | CHRNB2 (0.50) | RECQLTSHRCHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | RECQL 2090/4885TSHR 1902/4885ALDH1A1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.