SCHEMBL24322868

SCHEMBL24322868

N[C@H]1CCCN(CC(=O)N2CCCCC2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.48
CHRM2 P08172 3/20 0.43
CHRM4 P08173 3/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
HTT P42858 1/20 0.43
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ACE P12821 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999305 0.98 F10 (0.49) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL14603121 0.98 F10 (0.49) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL6985779 0.98 F10 (0.49) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL6982387 0.97 F10 (0.45) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL3276043 0.95 F10 (0.46) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL3276047 0.95 F10 (0.46) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL24324199 0.92 GAA (0.46) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL6979748 0.90 F10 (0.44) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL6979752 0.90 F10 (0.44) F10CHRM2CHRM4CHRM1CHRM3
SCHEMBL24323775 0.87 F10 (0.47) F10HTTGAAACEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN F10 1781/4885CHRM2 4880/4885CHRM4 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.