Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276043 | 1.00 | F10 (0.46) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6982387 | 0.98 | F10 (0.45) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7999305 | 0.97 | F10 (0.49) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14603121 | 0.97 | F10 (0.49) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6985779 | 0.97 | F10 (0.49) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24322868 | 0.95 | F10 (0.48) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6979752 | 0.92 | F10 (0.44) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6979748 | 0.92 | F10 (0.44) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24324199 | 0.90 | GAA (0.46) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24323775 | 0.85 | F10 (0.47) | F10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696328-B2 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| US-20090104670-A1 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | BRISTOL-MYERS SQUIBB COMPANY | 2009-04-23 | — | — | US | disclosed |
| US-7416876-B2 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme | BRISTOL-MEYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060275878-A1 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | BRISTOL-MYERS SQUIBB COMPANY | 2006-12-07 | — | — | US | disclosed |
| US-7119188-B2 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060149047-A1 | N-CARBOBENZYLOXY (N-CBZ)-DEPROTECTING ENZYME AND USES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-06 | — | — | US | disclosed |
| EP-1629087-A2 | N-CARBOBENZYLOXY (N-CBZ)-DEPROTECTING ENZYME AND USES THEREFOR | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2005001047-A2 | N-CARBOBENZYLOXY (N-CBZ)-DEPROTECTING ENZYME AND USES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |
| US-6828119-B2 | Deprotecting a hydroxide or amine; obtain sample, incubate with enzyme, remoe protecting group, recover amine | BRISTOL MYERS SQUIBB COMPANY | 2004-12-07 | — | — | US | disclosed |
| EP-1156803-A4 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20020123110-A1 | Enzymatic deprotection of amines and hydroxides | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-05 | — | — | US | disclosed |
| EP-1156803-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6297233-B1 | Lactam inhibitors of FXa and method | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-2000047207-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060275878-A1 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | CMBL, BCHE, NOTUM | F10 3288/4885CHRM2 4630/4885CHRM4 3732/4885 |
| US-20090104670-A1 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor | CMBL, BCHE, DNPEP | F10 3241/4885CHRM2 4764/4885CHRM4 4231/4885 |
| US-20060149047-A1 | N-CARBOBENZYLOXY (N-CBZ)-DEPROTECTING ENZYME AND USES THEREFOR | CMBL, BCHE, NOTUM | F10 3136/4885CHRM2 4628/4885CHRM4 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.