Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 5/20 | 0.34 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | NOS2 | P35228 | 5/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616045 | 1.00 | CYP1A2 (0.38) | CYP1A2EPHX2NOS3NOS1NOS2 | |
| SCHEMBL22810848 | 0.91 | EPHX2 (0.37) | CYP1A2EPHX2NOS3NOS1NOS2 | |
| SCHEMBL15185709 | 0.91 | EPHX2 (0.37) | CYP1A2EPHX2NOS3NOS1NOS2 | |
| SCHEMBL10972704 | 0.88 | CYP1A2 (0.46) | CYP1A2NOS3NOS1NOS2CHRNA7 | |
| SCHEMBL29065443 | 0.83 | CYP1A2 (0.52) | CYP1A2NOS3NOS1NOS2CHRNA7 | |
| SCHEMBL1703647 | 0.83 | EPHX2 (0.39) | EPHX2NCF1SIGMAR1 | |
| SCHEMBL26661 | 0.83 | EPHX2 (0.39) | EPHX2NCF1SIGMAR1 | |
| SCHEMBL7135021 | 0.83 | EPHX2 (0.39) | EPHX2NCF1SIGMAR1 | |
| SCHEMBL1703645 | 0.83 | EPHX2 (0.39) | EPHX2NCF1SIGMAR1 | |
| SCHEMBL467954 | 0.83 | EPHX2 (0.39) | EPHX2NCF1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362461-B1 | MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE | MODERNATX INC (US) | 2022-03-16 | — | — | EP | disclosed |