SCHEMBL467954

SCHEMBL467954

NC[C@@H]1CCC[C@H](CN)C1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
NCF1 P14598 1/20 0.38
CYP2D6 P10635 1/20 0.37
SIGMAR1 Q99720 1/20 0.35
PLG P00747 1/20 0.35
PLAT P00750 1/20 0.35
LMNA P02545 1/20 0.35
HRH4 Q9H3N8 2/20 0.32
ALOX5 P09917 1/20 0.32
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26661 1.00 EPHX2 (0.39) EPHX2NCF1CYP2D6SIGMAR1PLG
SCHEMBL1703645 1.00 EPHX2 (0.39) EPHX2NCF1CYP2D6SIGMAR1PLG
SCHEMBL7135021 1.00 EPHX2 (0.39) EPHX2NCF1CYP2D6SIGMAR1PLG
SCHEMBL1703647 1.00 EPHX2 (0.39) EPHX2NCF1CYP2D6SIGMAR1PLG
Hydrochloric Acid SCHEMBL25223266 0.97 EPHX2 (0.37) EPHX2NCF1CYP2D6SIGMAR1PLG
Ammonia Solution, Strong SCHEMBL9620353 0.97 EPHX2 (0.37) EPHX2NCF1CYP2D6SIGMAR1PLG
Ammonia Solution, Strong SCHEMBL20562887 0.97 EPHX2 (0.37) EPHX2NCF1CYP2D6SIGMAR1PLG
Hydrochloric Acid SCHEMBL9438734 0.97 EPHX2 (0.37) EPHX2NCF1CYP2D6SIGMAR1PLG
SCHEMBL5249610 0.94 PLG (0.42) EPHX2NCF1CYP2D6SIGMAR1PLG
SCHEMBL25602681 0.93 CYP2D6 (0.41) EPHX2NCF1CYP2D6SIGMAR1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021103550-A1 1,3-BISISOCYANATOMETHYLCYCLOHEXANE COMPOSITION AND OPTICAL RESIN PREPARED THEREFROM 万华化学集团股份有限公司 2021-06-03 WO claimed
CN-110982034-A 1, 3-diisocyanatomethylcyclohexane composition and optical resin prepared from same 万华化学集团股份有限公司 2020-04-10 CN claimed
EP-2094759-B1 EPOXY RESINS COMPRISING A CYCLOALIPHATIC DIAMINE CURING AGENT DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-18 EP claimed
US-20100029894-A1 POLYAMIDE POLYMER DOW GLOBAL TECHNOLOGIES LLC 2010-02-04 US claimed
EP-4739727-A1 CURING AGENT COMPOSITION COMPRISING SALTS OF THIOCYANATE Hilti Aktiengesellschaft (LI) 2026-05-13 EP disclosed
US-12597655-B2 Device for cooling and/or heating a battery of an electric or hybrid motor vehicle ARKEMA FRANCE (FR) 2026-04-07 US disclosed
EP-4702070-A1 TWO-COMPONENT EPOXY SYSTEMS Sika Technology AG (CH) 2026-03-04 EP disclosed
US-20250376561-A1 SHORT DIAMINE-BASED SEMI-CRYSTALLINE POLYAMIDE COMPOSITION HAVING A HIGH GLASS TRANSITION TEMPERATURE FOR A THERMOPLASTIC MATERIAL, PRODUCTION METHOD THEREOF AND USES OF SAME ARKEMA FRANCE (FR) 2025-12-11 US disclosed
US-20250297055-A1 METHOD FOR PREPARING AN EPOXY-DERIVED COVALENT ADAPTABLE NETWORK UNIVERSITEIT GENT (BE) 2025-09-25 US disclosed
US-12371539-B2 Use of a copolyamide composition as a matrix of filler material with glass fibres having a circular cross section for limiting warping ARKEMA FRANCE (FR) 2025-07-29 US disclosed
US-12344710-B2 Semi-crystalline copolyamides, moulding compounds comprising same and their use, and mouldings manufactured from same EMS-PATENT AG (CH) 2025-07-01 US disclosed
EP-4557461-A2 DEVICE FOR COOLING AND/OR HEATING A BATTERY OF AN ELECTRIC OR HYBRID MOTOR VEHICLE ARKEMA FRANCE (FR) 2025-05-21 EP disclosed
EP-1558659-A1 POLYURETHANE DISPERSION AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2005-08-03 EP disclosed
WO-2004041890-A9 POLYURETHANE DISPERSION AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2004-07-22 WO disclosed
WO-2004041890-A1 POLYURETHANE DISPERSION AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-05-21 WO disclosed
WO-2004041899-A1 POLYURETHANE COMPOUNDS AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-05-21 WO disclosed
US-20030191134-A1 Non-peptide somatostatin receptor ligands SHAPIRO GIDEON (US) 2003-10-09 US disclosed
EP-0780340-B1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORP (US) 2002-03-20 EP disclosed
US-6277911-B1 Transparent, colorless, amorphous copolyamides and molded articles made therefrom EMS INVENTA AG (CH) 2001-08-21 US disclosed
JP-2001115017-A POLYAMIDE RESIN COMPOSITION MITSUBISHI GAS CHEM CO INC 2001-04-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12597655-B2 Device for cooling and/or heating a battery of an electric or hybrid motor vehicle KIF5B, HSPB1, MYO3A EPHX2 1648/4885NCF1 2690/4885CYP2D6 2844/4885
US-20030191134-A1 Non-peptide somatostatin receptor ligands SSTR2, SSTR1, SSTR3 EPHX2 4673/4885NCF1 3526/4885CYP2D6 3992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.