Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322976 | 0.87 | CYP4F2 (0.37) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24322359 | 0.85 | RET (0.37) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24322176 | 0.83 | CYP4F2 (0.36) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL25698640 | 0.78 | PDE4B (0.39) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24322975 | 0.76 | CYP4F2 (0.39) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24322361 | 0.75 | PDE4B (0.37) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24322191 | 0.73 | CYP4F2 (0.36) | GAACYP4F2CYP4A11RETPDE4B | |
| SCHEMBL24013145 | 0.71 | CYP4F2 (0.49) | GAACYP4F2CYP4A11RETPDE7A | |
| SCHEMBL21152701 | 0.70 | GAA (0.51) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL15445676 | 0.69 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |