Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020327 | 0.73 | KDM4A (0.43) | KDM4CPDE10AMETAP2MAOAKDM4E | |
| SCHEMBL24323396 | 0.71 | DAO (0.47) | DAORAF1KDM4EMAPT | |
| SCHEMBL13024413 | 0.68 | PDE10A (0.44) | KDM4CPDE10AMETAP2DAOMAOA | |
| SCHEMBL1551334 | 0.67 | HSP90AB1 (0.43) | KDM4CPDE10ADAOKDM4EGAA | |
| SCHEMBL27498230 | 0.66 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL19967498 | 0.66 | KDM4C (0.42) | KDM4CPDE10AMETAP2DAOMAOA | |
| SCHEMBL27942177 | 0.65 | DAO (0.47) | KDM4CPDE10AMETAP2DAOMAOA | |
| SCHEMBL3939509 | 0.65 | RPS6KB2 (0.42) | KDM4CPDE10ADAOMAPT | |
| SCHEMBL27850680 | 0.65 | ELANE (0.46) | KDM4EGAAMAPT | |
| SCHEMBL6168905 | 0.64 | DAO (0.45) | KDM4CPDE10AMETAP2DAOMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |