Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600465 | 1.00 | DDB1 (0.35) | DDB1CRBNALDH1A1PLA2G1BMAPT | |
| SCHEMBL24324154 | 0.74 | CCR1 (0.47) | DDB1CRBNALDH1A1 | |
| SCHEMBL6914165 | 0.69 | NPC1 (0.38) | ALDH1A1PLA2G1BMAPTATG4B | |
| SCHEMBL3677969 | 0.69 | NPC1 (0.38) | ALDH1A1PLA2G1BMAPTATG4B | |
| SCHEMBL15469665 | 0.68 | DDB1 (0.37) | DDB1CRBNMAPT | |
| SCHEMBL7914425 | 0.65 | CCR1 (0.42) | DDB1CRBN | |
| SCHEMBL30322466 | 0.64 | DDB1 (0.39) | DDB1CRBN | |
| SCHEMBL30503575 | 0.64 | APP (0.42) | DDB1CRBNMAPT | |
| SCHEMBL22323347 | 0.64 | DDB1 (0.39) | DDB1CRBN | |
| SCHEMBL30545112 | 0.64 | DDB1 (0.39) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |