Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21284819 | 0.76 | CCR1 (0.45) | CCR1ALDH1A1BRD4BRPF1BRD9 | |
| SCHEMBL29600465 | 0.74 | DDB1 (0.35) | DDB1CRBNALDH1A1 | |
| SCHEMBL24323565 | 0.74 | DDB1 (0.35) | DDB1CRBNALDH1A1 | |
| SCHEMBL7914425 | 0.71 | CCR1 (0.42) | CCR1CYP2A6DDB1CRBNBRD4 | |
| SCHEMBL30322466 | 0.69 | DDB1 (0.39) | CYP2A6DDB1CRBNPIK3CB | |
| SCHEMBL22323347 | 0.69 | DDB1 (0.39) | CYP2A6DDB1CRBNPIK3CB | |
| SCHEMBL15091312 | 0.69 | PIK3CB (0.44) | CYP2A6DDB1CRBNPIK3CB | |
| SCHEMBL30545112 | 0.69 | DDB1 (0.39) | CYP2A6DDB1CRBNPIK3CB | |
| SCHEMBL30503575 | 0.69 | APP (0.42) | CYP2A6DDB1CRBNPIK3CB | |
| SCHEMBL3754475 | 0.69 | DDB1 (0.39) | CYP2A6DDB1CRBNPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |