Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADCY10 | Q96PN6 | 7/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600361 | 1.00 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1LMNAKDM4EKMT2A | |
| SCHEMBL22501986 | 0.86 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 | |
| Hydrochloric Acid SCHEMBL22502036 | 0.84 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 | |
| SCHEMBL3946692 | 0.79 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1LMNAKDM4EADCY10 | |
| SCHEMBL29566525 | 0.79 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1LMNAKDM4EADCY10 | |
| SCHEMBL29567149 | 0.78 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1LMNAKDM4EADCY10 | |
| SCHEMBL22502009 | 0.77 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 | |
| SCHEMBL24298190 | 0.74 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 | |
| SCHEMBL3945480 | 0.74 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 | |
| SCHEMBL15757130 | 0.74 | NUDT1 (0.64) | HSP90AA1HSP90AB1KDM4EKMT2AADCY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |