⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235304 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL17201496 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL4779247 | 0.74 | — | — | |
| SCHEMBL670675 | 0.74 | — | — | |
| SCHEMBL9272949 | 0.73 | ALOX5 (0.35) | — | |
| SCHEMBL8585691 | 0.73 | — | — | |
| SCHEMBL234885 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL236020 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL8064324 | 0.69 | TSHR (0.41) | — | |
| SCHEMBL253633 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064887-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2008-03-13 | — | — | US | claimed |
| US-20030229135-A1 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbonyl]-5-oxazolidine carboxylic acids | DABUR PHARMA LIMITED (IN) | 2003-12-11 | — | — | US | claimed |
| US-20230096051-A1 | CGRP ANTIGONISTS USEFUL AS TRACER COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | ELI LILLY AND COMPANY | 2023-03-30 | — | — | US | disclosed |
| WO-2021118887-A1 | CGRP ANTIGONISTS USEFUL AS TRACER COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | ELI LILLY AND COMPANY (US) | 2021-06-17 | — | — | WO | disclosed |
| US-RE44768-E1 | Rapamycin hydroxyesters | WYETH LLC (US) | 2014-02-18 | — | — | US | disclosed |
| US-8088564-B2 | Base soluble polymers for photoresist compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2004725-B1 | BASE SOLUBLE POLYMERS FOR PHOTORESIST COMPOSITIONS | AZ ELECTRONIC MATERIALS USA (US) | 2009-10-07 | — | — | EP | disclosed |
| US-7550249-B2 | Base soluble polymers for photoresist compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7537879-B2 | Chemically amplified, sensitive to wavelengths (300 nm - 100 nm); comprises a novel polymer with a sulfone group pendant from a polymer backbone that is insoluble in an aqueous alkaline solution and has acidic moiety protected with acid labile group, and a compound that producing an acid upon irradiation | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2009-05-26 | — | — | US | disclosed |
| US-20090061347-A1 | BASE SOLUBLE POLYMERS FOR PHOTORESIST COMPOSITIONS | MERCK PATENT GMBH (DE) | 2009-03-05 | — | — | US | disclosed |
| US-20090042148-A1 | Photoresist Composition for Deep UV and Process Thereof | AZ ELECTRONIC MATERIALS USA CORP. | 2009-02-12 | — | — | US | disclosed |
| WO-1994001104-A1 | NOVEL CHOLESTEROL LOWERING COMPOUNDS | MERCK & CO., INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5258401-A | Fused ring oxygen compounds, anticholesterol | MERCK & CO., INC. (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1992020336-A2 | NOVEL CHOLESTEROL LOWERING COMPOUNDS | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0512865-A2 | Novel cholesterol lowering compounds | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0428605-A1 | SYNTHETIC RECEPTOR ANALOGUES. | SYMBICOM AB (SE) | 1991-05-29 | — | — | EP | disclosed |
| US-4918170-A | Process for producing gangliosides | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4914035-A | REACTING ALKYLTHIOSIALIC ACID DERIVATIVE WITH HYDROXY COMPOUND AT LOW TEMPERATURE IN POLAR SOLVENT WITH THIOPHILIC PROMOTER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| WO-1990001488-A1 | SYNTHETIC RECEPTOR ANALOGUES | SYMBICOM AKTIEBOLAG (SE) | 1990-02-22 | — | — | WO | disclosed |
| EP-0102239-B1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF CARBAPENEM ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |