Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030162 | 1.00 | DPP4 (0.55) | DPP4POLBALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30158110 | 0.98 | DPP4 (0.54) | DPP4POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19263522 | 0.81 | RXFP1 (0.52) | POLBALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL20901706 | 0.81 | TSHR (0.55) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1534257 | 0.81 | TDP1 (0.49) | DPP4POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16623045 | 0.81 | RXFP1 (0.52) | POLBALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL18010611 | 0.81 | TSHR (0.55) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL20901666 | 0.81 | TSHR (0.55) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL16623003 | 0.81 | RXFP1 (0.52) | POLBALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11891161 | 0.81 | TP53 (0.51) | DPP4POLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | DPP4 532/4885POLB 4461/4885ALDH1A1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.