⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24323203 | 0.86 | — | — | |
| SCHEMBL16225582 | 0.73 | — | — | |
| SCHEMBL16225234 | 0.73 | — | — | |
| SCHEMBL16225233 | 0.73 | — | — | |
| SCHEMBL563310 | 0.68 | CA2 (0.30) | — | |
| SCHEMBL24323209 | 0.68 | — | — | |
| SCHEMBL17540958 | 0.67 | — | — | |
| SCHEMBL19018906 | 0.67 | — | — | |
| SCHEMBL17541866 | 0.67 | — | — | |
| SCHEMBL24529290 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225765-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |
| CN-107531829-A | For the product for preparing the method for the block copolymer comprising the first polyolefin block and second polymer block and being obtained from methods described | SABIC环球技术有限责任公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107207712-A | Process for preparing a graft copolymer comprising a polyolefin backbone and one or more polymeric side chains and product obtained from said process | SABIC环球技术有限责任公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-106831389-A | The preparation method of carboxylic acid compound | 中国科学技术大学 | 2017-06-13 | — | — | CN | disclosed |
| CN-105473658-A | Polymer composition | SAUDI BASIC IND CORP | 2016-04-06 | — | — | CN | disclosed |
| CN-105408387-A | Block copolymer and process for preparing the same | SAUDI BASIC IND CORP | 2016-03-16 | — | — | CN | disclosed |
| CN-105263984-A | Method for preparing a polyester | SAUDI BASIC IND CORP | 2016-01-20 | — | — | CN | disclosed |
| CN-105143303-A | Process for preparing a copolymer | SAUDI BASIC IND CORP | 2015-12-09 | — | — | CN | disclosed |
| CN-103649072-A | 4h-thieno[3,2-c]chromene-based inhibitors of notum pectinacetylesterase and methods of their use | LEXICON PHARMACEUTICALS INC | 2014-03-19 | — | — | CN | disclosed |
| CN-101589041-A | Nitrogen-containing heterocyclic compounds and methods of use thereof | SCHERING CORP (US) | 2009-11-25 | — | — | CN | disclosed |
| CN-101175759-A | Nitrogen-containing heterocyclic compounds and methods of use thereof | SCHERING CORP (US) | 2008-05-07 | — | — | CN | disclosed |