SCHEMBL24324810

SCHEMBL24324810

CC(=O)C(=O)N1CCC2(CC1)CC(=O)C(c1c(C)cc(-c3ccc(C#N)cn3)cc1C)C(=O)C2

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 2/20 0.35
FASN P49327 7/20 0.35
CYP1A2 P05177 2/20 0.34
TSHR P16473 2/20 0.34
MEN1 O00255 1/20 0.34
CYP2C9 P11712 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP2D6 P10635 1/20 0.34
GRM5 P41594 1/20 0.34
EGLN1 Q9GZT9 2/20 0.34
CNR2 P34972 2/20 0.34
P2RX7 Q99572 1/20 0.33
KCNJ1 P48048 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21361283 0.93 CYP1A2 (0.41) ACACAFASNCYP1A2TSHRMEN1
SCHEMBL24324819 0.91 FASN (0.35) ACACAFASNEGLN1CNR2P2RX7
SCHEMBL21361291 0.89 FASN (0.37) ACACAFASN
SCHEMBL21361287 0.89 IRAK4 (0.37) ACACAFASNCYP2C9EGLN1CNR2
SCHEMBL24324693 0.88 FASN (0.39) FASNEGLN1CNR2
SCHEMBL24325170 0.88 FASN (0.40) FASNCYP2C9CNR2P2RX7PIK3CA
SCHEMBL21361286 0.88 IRAK4 (0.36) ACACAFASNCYP2C9CNR2KCNJ1
SCHEMBL21361223 0.88 JAK2 (0.37) FASNCNR2P2RX7PIK3CAMTOR
SCHEMBL21361301 0.87 GRM5 (0.45) ACACAFASNCYP2D6GRM5
SCHEMBL22908414 0.87 CYP1A2 (0.41) ACACAFASNCYP1A2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220117228-A1 SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220117228-A1 SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES DDT, DHFR, CCNB3 ACACA 1303/4885FASN 2143/4885CYP1A2 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.