Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 6/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611549 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12303359 | 0.95 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL195591 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL2900514 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL25342477 | 0.86 | CA12 (0.50) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL31024702 | 0.86 | CA12 (0.50) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL23906095 | 0.85 | CA12 (0.48) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL3616519 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL28149249 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL16858435 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357253-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2023-11-09 | — | — | US | disclosed |
| US-20230357253-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2023-11-09 | — | — | US | disclosed |
| US-20230357253-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE | 2023-11-09 | — | — | US | disclosed |
| CN-116940567-A | Agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2023-10-24 | — | — | CN | disclosed |
| EP-4208260-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | The Scripps Research Institute (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022051765-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-03-10 | — | — | WO | disclosed |
| WO-2022051765-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357253-A1 | AGONISTS OF STIMULATOR OF INTERFERON GENES STING | STING1, IRF3, CGAS | KDM4E 4074/4885ALDH1A1 4453/4885GAA 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.