Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 7/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195591 | 0.94 | KDM4E (0.61) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL2900514 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL195076 | 0.84 | GAA (0.57) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL19554228 | 0.84 | ABL1 (0.56) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL24324843 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL29611549 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL3616519 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL376859 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL12303359 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1ABL1GAAHSD17B10 | |
| SCHEMBL29813036 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1ABL1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288761-B | The new method of one kind synthesis derovatives of 1,2,3,4 quinazoline 2,4 | 浙江华海药业股份有限公司 | 2017-08-11 | — | — | CN | disclosed |