SCHEMBL24326871

SCHEMBL24326871

C=C(C)C(=O)OCCOC(=O)NCCC(C)(C)CC(C)CNC(=O)OCCOC(=O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
TSHR P16473 3/20 0.32
HRH4 Q9H3N8 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21064764 1.00 THRB (0.33) THRBTSHRHRH4HRH3ACHE
SCHEMBL274925 0.94 THRB (0.37) THRBTSHRHRH4HRH3ACHE
SCHEMBL16328352 0.90 THRB (0.34) THRBTSHRHRH4HRH3ACHE
SCHEMBL24386246 0.90 THRB (0.34) THRBTSHRHRH4HRH3ACHE
SCHEMBL24326826 0.90 THRB (0.34) THRBTSHRHRH4HRH3ACHE
SCHEMBL15292049 0.87 THRB (0.35) THRBTSHRHRH4HRH3ACHE
SCHEMBL21579580 0.87 TSHR (0.42) THRBTSHRHRH4HRH3ACHE
SCHEMBL14564454 0.87 THRB (0.32) THRBTSHRHRH4HRH3ACHE
SCHEMBL13270075 0.86 HRH3 (0.34) THRBTSHRHRH4HRH3ACHE
SCHEMBL25545839 0.86 TSHR (0.35) THRBTSHRHRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220118787-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2022-04-21 US disclosed