SCHEMBL24326924

SCHEMBL24326924

O=C(c1cnc(NC2CCc3nccnc32)nc1)N1CCC2(CCOCC2)C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 20/20 0.57
BTD P43251 7/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24326822 0.86 VNN1 (0.58) VNN1BTD
SCHEMBL24326948 0.86 VNN1 (0.58) VNN1BTD
SCHEMBL24326947 0.86 VNN1 (0.58) VNN1BTD
SCHEMBL24326939 0.85 VNN1 (0.54) VNN1BTD
SCHEMBL24326929 0.83 VNN1 (0.60) VNN1BTD
SCHEMBL24326938 0.82 VNN1 (0.52) VNN1BTD
SCHEMBL24327697 0.82 VNN1 (0.52) VNN1BTD
SCHEMBL24326943 0.82 VNN1 (0.55) VNN1BTD
SCHEMBL24326815 0.81 VNN1 (0.58) VNN1BTD
SCHEMBL24326913 0.81 VNN1 (0.57) VNN1BTD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219479-A1 PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF Shanghai Meiyue Biotech Development Co., Ltd. (CN) 2023-08-02 EP disclosed
WO-2022063197-A1 PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF 上海美悦生物科技发展有限公司 2022-03-31 WO disclosed
WO-2022063333-A1 PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF 上海美悦生物科技发展有限公司 2022-03-31 WO disclosed