Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26844465 | 0.89 | DPP4 (0.38) | ACEELANEDPP4HTR1AHTR7 | |
| SCHEMBL22955221 | 0.85 | DPP4 (0.37) | DPP4 | |
| SCHEMBL12463609 | 0.83 | ELANE (0.41) | ACEELANEDPP4CASP1CASP4 | |
| SCHEMBL26616459 | 0.81 | ERAP2 (0.47) | ACE | |
| SCHEMBL3726967 | 0.80 | DPP4 (0.42) | ELANEDPP4CASP1CASP4CASP5 | |
| SCHEMBL25717179 | 0.78 | ACE (0.41) | ACEELANECASP1CASP4CASP5 | |
| SCHEMBL8144172 | 0.77 | ELANE (0.54) | ELANEDPP4CASP1CASP4CASP5 | |
| SCHEMBL24051779 | 0.77 | ELANE (0.42) | ACEELANEF2 | |
| SCHEMBL15196612 | 0.76 | ELANE (0.42) | ACEELANECASP1 | |
| SCHEMBL14421202 | 0.76 | ELANE (0.42) | ELANEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |