Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726967 | 0.86 | DPP4 (0.42) | ELANECASP1DPP4DPP8DPP9 | |
| SCHEMBL7804414 | 0.86 | ELANE (0.56) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL13748696 | 0.86 | ELANE (0.56) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8167988 | 0.86 | DPP4 (0.45) | ELANECMA1DPP4DPP8DPP9 | |
| SCHEMBL24051779 | 0.84 | ELANE (0.42) | ELANEXIAPBIRC3BIRC2PEPD | |
| SCHEMBL14421202 | 0.83 | ELANE (0.42) | ELANEDPP4DPP8DPP9FAP | |
| SCHEMBL20388035 | 0.82 | DPP4 (0.40) | ELANECASP1DPP4DPP8DPP9 | |
| SCHEMBL7944997 | 0.82 | DPP4 (0.40) | ELANEDPP4DPP8DPP9FAP | |
| SCHEMBL806180 | 0.82 | ELANE (0.42) | ELANECMA1 | |
| SCHEMBL8055611 | 0.82 | ELANE (0.42) | ELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |