Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159020 | 0.89 | OPRM1 (0.35) | — | |
| SCHEMBL22317566 | 0.88 | CYP2D6 (0.36) | CYP2D6 | |
| SCHEMBL19853482 | 0.88 | CYP2D6 (0.34) | CYP2D6ALDH1A1 | |
| SCHEMBL27277294 | 0.85 | — | — | |
| SCHEMBL14818604 | 0.84 | CYP2D6 (0.38) | CYP2D6ALDH1A1 | |
| SCHEMBL25465545 | 0.84 | — | — | |
| SCHEMBL20840885 | 0.82 | — | — | |
| SCHEMBL24861048 | 0.81 | — | — | |
| SCHEMBL24313443 | 0.81 | — | — | |
| SCHEMBL27099573 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022063197-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | 上海美悦生物科技发展有限公司 | 2022-03-31 | — | — | WO | disclosed |
| WO-2022063333-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | 上海美悦生物科技发展有限公司 | 2022-03-31 | — | — | WO | disclosed |