SCHEMBL24328755 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK1	P28482	1/20	0.39

▸	PIM1	P11309	5/20	0.37

▸	CNR1	P21554	1/20	0.36

▸	CNR2	P34972	1/20	0.36

▸	JAK2	O60674	1/20	0.36

▸	JAK1	P23458	1/20	0.36

▸	TYK2	P29597	1/20	0.36

▸	JAK3	P52333	1/20	0.36

▸	AHR	P35869	1/20	0.36

▸	AXL	P30530	8/20	0.36

▸	FGFR3	P22607	1/20	0.34

▸	KDR	P35968	1/20	0.34

▸	PRMT5	O14744	2/20	0.34

▸	WDR77	Q9BQA1	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24327387	0.82	AHR (0.42)	MAPK1PIM1CNR1CNR2JAK2
SCHEMBL24327848	0.74	JAK2 (0.43)	CNR1CNR2JAK2JAK1TYK2
SCHEMBL24328754	0.74	JAK2 (0.39)	CNR1CNR2JAK2JAK1TYK2
SCHEMBL29738280	0.71	AHR (0.41)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL24539605	0.71	JAK2 (0.48)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL24539496	0.71	JAK2 (0.48)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL24539411	0.69	JAK2 (0.48)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL28951079	0.69	JAK2 (0.48)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL23390448	0.69	AHR (0.42)	MAPK1CNR1CNR2JAK2JAK1
SCHEMBL23390451	0.69	AHR (0.42)	MAPK1CNR1CNR2JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022078356-A1	HETEROAROMATIC AHR INHIBITOR	山东轩竹医药科技有限公司	2022-04-21	—	—	WO	disclosed